03, Publications
Read the work.
83 selected papers, reviews and preprints from the group, 2025 to 2003 — spanning mucosal immunology, microbial ecology, oral vaccines and quantitative biology. Search by title, author or journal.
2025
Breathprints of the Barn: The Future of Livestock Research and Monitoring with Exhalomics
M. Niu, U. Arshad, M.Z. Islam, M.A. Barrientos-Blanco, E. Slack, S. Giannoukos and R. Zenobi
Annu. Rev. Anim. Biosci. 2026. 14:4.1–4.23
2025Quantifying the varying harvest of fermentation products from the human gut microbiota
Markus Arnoldini, Richa Sharma, Claudia Moresi, Griffin Chure, Julien Chabbey, Emma Slack, Jonas Cremer
Cell, Volume 188, Issue 19, 5332 - 5342.e16
2025Transcriptomic profiles of single-copy marker genes enable predicting bacterial growth states in microbial communities
M. L. Staeubli, H. J. Ruscheweyh, G. Greter, M. Dmitrijeva, S. Miravet-Verde, M. Arnoldini, W. D. Hardt, E. Slack, A. Sintsova, S. Sunagawa
bioRxiv preprint
2025In vitro and in vivo selection and cost of bacteriophage resistance on natural Escherichia coli
Luís Leónidas Cardoso, Marla Sofie Gaissmaier, Alexandra von Strempel, Tim Keys, Monica Steffi Matchado, Marta Salvado Silva, Diana Ring, Emma Slack, Bärbel Stecher
microLife, Volume 6, 2025
2025The natural diversity of E. coli transporter-dependent capsules
Carine Roese Mores, Samuel Miravet-Verde, Elisabetta Cacace, Christoph Rutschmann, Chia-Wei Lin, Hans J. Ruscheweyh, Aline Cuenod, Elisa Cappio Barazzone, Enora Marrec, Kateryna Vershynina, Raffael Schumann, Dan J. Bower, Mario Schubert, Adrian Egli, Timm Fiebig, Emma Slack, Shinichi Sunagawa, Timothy G. Keys
2025Emergent spatial structure in the gut microbiota is driven by bacterial growth and gut contractions
Giorgia Greter, Sebastian Hummel, Daria Künzli, Naomi Dünki, Niina Ruoho, Patricia Burkhardt, Suwannee Ganguillet, Milad Radiom, Claudia Moresi, Leanid Laganenka, Wolf-Dietrich Hardt, Steffen Geisel, Sebastian Jordi, Benjamin Misselwitz, Bahtiyar Yilmaz, Jonasz Slomka, Eleonora Secchi, Roman Stocker, Emma Slack, Markus Arnoldini
bioRxiv preprint
2025Immunophenotyping of very preterm infants at risk of developing sepsis and necrotizing enterocolitis
Johannes Trück, Sophie Strasser, Valentin von Niederhäusern, Noëmi Meier, Jasmin Simma, Emma Slack, Giancarlo Natalucci, Claudia Knöpfli
Research Square preprint
2025Mucosal B cell memory selection integrates tissue-specific microbial cues via the IgA BCR
Maria Pia Holgado, Samuel Origlio, Lucas Bertoia, Myriam Moussa, Apurwa Trivedi, Frederic Fiore, Ana Zarubica, Emma Slack, Michelle A. Linterman, Michel Cogné, Claude Gregoire, Mauro Gaya
bioRxiv preprint
2025LC-Inspector: a simple open-source viewer for targeted hyphenated mass spectrometry analysis
Mateusz Fido, Etienne Hoesli, Elisa Cappio Barazzone, Renato Zenobi, Emma Slack
bioRxiv preprint
2025Investigating Polyreactivity of CD4+ T Cells to the Intestinal Microbiota
Ahmed Saadawi, Florian Mair, Esther Rosenwald, Daniel Hoces, Emma Slack, Manfred Kopf
Eur J Immunol. (2025) 55:e202451484
2025Vaccine-enhanced competition permits rational bacterial strain replacement in the gut
Verena Lentsch, Aurore Woller, Andre Rocker, Selma Aslani, Claudia Moresi, Niina Ruoho, Louise Larsson, Stefan A. Fattinger, Nicolas Wenner, Elisa Cappio Barazzone, Wolf-Dietrich Hardt, Claude Loverdo, Médéric Diard, Emma Slack
Science Volume 388, Issue 6742, pp. 74-81 (2025)
2025Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition
Sanne Kroon, Dejan Malcic, Lena Weidert, Lea Bircher, Leonardo Boldt, Philipp Christen, Patrick Kiefer, Anna Sintsova, Bidong D. Nguyen, Manja Barthel, Yves Steiger, Melanie Clerc, Mathias K.-M. Herzog, Carmen Chen, Ersin Gül, Benoit Guery, Emma Slack, Shinichi Sunagawa, Julia A. Vorholt, Lisa Maier, Christophe Lacroix, Annika Hausmann & Wolf-Dietrich Hardt
Nature Communications volume 16, Article number: 2760 (2025)
2025Active eosinophils regulate host defence and immune responses in colitis
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás G Núñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle C Arnold
Nature 615, 151-157 (2023)
2025DMB labelling for detection and analysis of capsular polysaccharides
Christoph Rutschmann, Kateryna Vershynina, Corina Mathew, Lucas Piëch, Małgorzata Sulewska, Philipp E Schilling, Nicolas Wenner, Louise Larsson, Anouk Bertola, Elisa Cappio Barazzone, Ioana Domocos, Carine Roese Mores, Jackie Raisse Ndem-Galbert, Yagmur Turgay, Raffael Schumann, Shirin de Viragh, Hayley Lavender, Chris Tang, Médéric Diard, Shinichi Sunagawa, Michael Wetter, Timm Fiebig, Emma Slack, Timothy G Keys
bioRxiv preprint
2025Relaxation of mucosal fibronectin fibers in late gut inflammation following neutrophil infiltration in mice
Ronja Rappold, Konstantinos Kalogeropoulus, Gianna La Regina, Ulrich auf dem Keller, Emma Slack, Viola Vogel
npj Biological Physics and Mechanics 2, 4 (2025)
20252024
Diagnosing and engineering gut microbiomes
Elisa Cappio Barazzone, Médéric Diard, Isabelle Hug, Louise Larsson, Emma Slack
EMBO Mol Med (2024)16: 2660 - 2677
2024Salmonella Typhimurium screen identifies shifts in mixed-acid fermentation during gut colonization
Bidong D Nguyen, Anna Sintsova, Christopher Schubert, Andreas Sichert, Clio Scheidegger, Jana Näf, Julien Huttman, Verena Lentsch, Tim Keys, Christoph Rutschmann, Philipp Christen, Patrick Kiefer, Philipp Keller, Manja Barthel, Miguelangel Cuenca, Beat Christen, Uwe Sauer, Emma Slack, Julia A Vorholt, Shinichi Sunagawa, Wolf-Dietrich Hardt
Volume 32, Issue 10, 9 October 2024, Pages 1758-1773
2024Microbial hoolIgAn dismantles gut defenses
Emma Slack
Comment, Science, Vol 385, Issue 6716, pp. 1418 - 1420, Sept 26 2024
2024Host control of the microbiome: Mechanisms, evolution, and disease
Jacob Wilde, Emma Slack, Kevin R Foster
Science, Vol 385, Issue 6706, Jul 19 2024
2024Acute targeted induction of gut-microbial metabolism affects host clock genes and nocturnal feeding
Giorgia Greter, Claudia Moresi, Stefanie Oswald, Alice de Wouters d'Oplinter, Daria Künzli, Elisa Cappio Barazzone, Jiayi Lan, Emma Slack, Markus Arnoldini
eLife reviewed preprint, September 2024
2024Salmonella-driven intestinal edema in mice is characterized by tensed fibronectin fibers
Ronja Rappold, Konstantinos Kalogeropoulos, Ulrich auf dem Keller, Viola Vogel, Emma Slack
FEBS J., 2024 Mar 15
2024Surface Cross-Linking by Macromolecular Tethers Enhances Virus-like Particles’ Resilience to Mucosal Stress Factors
Ahmed Ali, Suwannee Ganguillet, Yagmur Turgay, Timothy G. Keys, Erika Causa, Ricardo Fradique, Viviane Lutz-Bueno, Serge Chesnov, Chia-Wei Tan-Lin, Verena Lentsch, Jurij Kotar, Pietro Cicuta, Raffaele Mezzenga, Emma Slack, and Milad Radiom
ACS Nano 2024 18 (4), 3382-3396
2024Quantifying the daily harvest of fermentation products from the human gut microbiota
Markus Arnoldini, Richa Sharma, Claudia Moresi, Griffin Chure, Julien Chabbey, Emma Slack and Jonas Cremer
bioRxiv preprint
20242023
From microbiome composition to functional engineering, one step at a time
Sebastian Dan Burz, Senka Causevic, Alma Dal Co, Marija Dmitrijeva, Philipp Engel, Daniel Garrido-Sanz, Gilbert Greub, Siegfried Hapfelmeier, Wolf-Dietrich Hardt, Vassily Hatzimanikatis, Clara Margot Heiman, Mathias Klaus-Maria Herzog, Alyson Hockenberry, Christoph Keel, Andreas Keppler, Soon-Jae Lee, Julien Luneau, Lukas Malfertheiner, Sara Mitri, Bidong Ngyuen, Omid Oftadeh, Alan R. Pacheco, François Peaudecerf, Grégory Resch, Hans-Joachim Ruscheweyh, Asli Sahin, Ian R. Sanders, Emma Slack, Shinichi Sunagawa, Janko Tackmann, Robin Tecon, Giovanni Stefano Ugolini, Jordan Vacheron, Jan Roelof van der Meer, Evangelia Vayena, Pascale Vonaesch, Julia A. Vorholt
Microbiology and Molecular Biology Reviews, December 2023, Volume 87, Issue 4
2023Mechanical tuning of virus-like particles
Milad Radiom, Tim Keys, Yagmur Turgay, Ahmed Ali, Swapan Preet, Serge Chesnov, Viviane Lutz-Bueno, Emma Slack, Raffaele Mezzenga
Journal of Colloid and Interface Science, vol. 634, p.963-971
2023Microbiomes in Neverland
Emma Slack, Nicholas A. Bokulich
Cell Host and Microbe, vol. 31(4), p. 461-463
2023Nanoscale clustering by O-antigen-Secretory Immunoglobulin-A binding limits outer membrane diffusion by encaging individual Salmonella cells
Alyson Hockenberry, Milad Radiom, Markus Arnoldini, Yagmur Turgay, Matthew Dunne, Jozef Adamcik, Beth Stadtmueller, Raffaele Mezzenga, Martin Ackermann, Emma Slack
bioRxiv. 2023 Jul 14:2023.07.13.548943
2023Non-invasive monitoring of microbiota and host metabolism using secondary electrospray ionization-mass spectrometry
Jiayi Lan, Giorgia Greter, Bettina Streckenbach, Benedikt Wanner, Markus Arnoldini, Renato Zenobi, Emma Slack
Cell Reports Methods, Volume 3, Issue 8, 1000539
2023“EvoVax” – A rationally designed inactivated Salmonella Typhimurium vaccine induces strong and long-lasting immune responses in pigs
Verena Lentsch, Selma Aslani, Thomas Echtermann, Swapan Preet, Elisa Cappio Barazzone, Daniel Hoces, Claudia Moresi, Dolf Kümmerlen, Emma Slack
Vaccine, Volume 41, Issue 38, Pages 5545-5552
2023The microbiota conditions a gut milieu that selects for wild-type Salmonella Typhimurium virulence
Ersin Gül, Erik Bakkeren, Guillem Salazar, Yves Steiger, Andrew Abi Younes, Melanie Clerc, Philipp Christen, Stefan A. Fattinger, Bidong D. Nguyen, Patrick Kiefer, Emma Slack, Martin Ackermann, Julia A. Vorholt, Shinichi Sunagawa, Médéric Diard, Wolf-Dietrich Hardt
PLoS Biology 21(8): e3002253
2023License to Clump: Secretory IgA Structure-Function Relationships Across Scales
Alyson Hockenberry, Emma Slack, Beth M Stadtmueller
Annual Review of Microbiology, vol. 77, p.645-668 (2023)
2023Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota
Daniel Hoces, Giorgia Greter, Markus Arnoldini, Melanie L. Stäubli, Claudia Moresi, Anna Sintsova, Sara Berent, Isabel Kolinko, Florence Bansept, Aurore Woller, Janine Häfliger, Eric Martens, Wolf-Dietrich Hardt, Shinichi Sunagawa, Claude Loverdo, Emma Slack
eLife Sciences Publication Ltd. Camebridge UK, Infectious Diseases and Microbiology (2023)
20232022
Mechanical tuning of virus-like particles
Milad Radiom, Tim Keys, Yagmur Turgay, Ahmed Ali, Swapan Preet, Serge Chesnov, Viviane Lutz-Bueno, Emma Slack, Raffaele Mezzenga
Journal of Colloid and Interface Science, vol. 634, p. 963-971 (2023)
2022Active eosinophils regulate host defence and immune responses in colitis
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E. Acar, Nicolás G. Núñez, Daniel Crepaz, Kristina Handler, Vivian P. Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E. Moor & Isabelle C. Arnold
Nature vol. 615, p. 151–157 (2023)
2022Resistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution
Emma Slack and Médéric Diard
Mucosal Immunology, Nature Publishing Group (2022), Volume 15, Issue 6, P1188–1198
2022Microbiome-based interventions to modulate gut ecology and the immune system
Thomas C. A. Hitch, Lindsay J. Hall, Sarah Kate Walsh, Gabriel E. Leventhal, Emma Slack, Tomas de Wouters, Jens Walter and Thomas Clavel
Mucosal Immunology, Nature Publishing Group (2022), Volume 15, Issue 6, P1095-1113
2022Metabolic reconstitution of germ-free mice by a gnotobiotic microbiota varies over the circadian cycle
Daniel Hoces, Jiayi Lan, Wenfei Sun, Tobias Geiser, Melanie L. Stäubli, Elisa Cappio Barazzone, Markus Arnoldini, Tenagne D. Challa, Manuel Klug, Alexandra Kellenberger, Sven Nowok, Erica Faccin, Andrew J. Macpherson, Bärbel Stecher, Shinichi Sunagawa, Renato Zenobi, Wolf-Dietrich Hardt, Christian Wolfrum, Emma Slack
PLoS Biology, 2022, 20(9):e3001743
20222021
IL-1 Mediates Microbiome-Induced Inflamm-Ageing of Hematopoietic Stem Cells in Mice
Larisa Vladimirovna Kovtonyuk, Francisco Caiado, Santiago Garcia-Martin, Eva-Maria Manz, Patrick Michael Helbling, Hitoshi Takizawa, Steffen Boettcher, Fatima Al-Shahrour, Cesar Nombela-Arrieta, Emma Slack and Markus G. Manz
Blood, 2021
2021Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity
Simona P. Pfister, Olivier P. Schären, Luca Beldi, Andrea Printz, Matheus D. Notter, Mohana Mukherjee, Hai Li, Julien P. Limenitakis, Joel P. Werren, Disha Tandon, Miguelangel Cuenca, Stefanie Hagemann, Stephanie S. Uster, Miguel A. Terrazos, Mercedes Gomez de Agüero, Christian M. Schürch, Fernanda M. Coelho, Roy Curtiss, Emma Slack, Maria L. Balmer and Siegfried Hapfelmeier
Nature Communications, vol 11, 2021
2021A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
Médéric Diard, Erik Bakkeren, Verena Lentsch, Andrea Rocker, Nahimi Amare Bekele, Daniel Hoces, Selma Aslani, Markus Arnoldini, Flurina Böhi, Kathrin Schumann-Moor, Jozef Adamcik, Luca Piccoli, Antonio Lanzavecchia, Beth M. Stadtmueller, Nicholas Donohue, Marjan W. van der Woude, Alyson Hockenberry, Patrick H. Viollier, Laurent Falquet, Daniel Wüthrich, Ferdinando Bonfiglio, Claude Loverdo, Adrian Egli, Giorgia Zandomeneghi, Raffaele Mezzenga, Otto Holst, Beat H. Meier, Wolf-Dietrich Hardt and Emma Slack
Nature Microbiology, 2021
2021Prospective Validation of CD-62L (L-Selectin) as Marker of Durable Response to Infliximab Treatment in Patients With Inflammatory Bowel Disease: A 5-Year Clinical Follow-up
Francisco Bravo, Jamie A. Macpherson, Emma Slack, Nicolas Patuto, Julia Cahenzli, Kathy D. McCoy, Andrew J. Macpherson, and Pascal Juillerat
Clinical Translational Gastroenterology, 12(2):p e00298 February 2021
2021Reproducible Colonization of Germ-Free Mice With the Oligo-Mouse-Microbiota in Different Animal Facilities
Claudia Eberl, Diana Ring, Philipp C. Münch, Markus Beutler, Marijana Basic, Emma C. Slack, Martin Schwarzer, Dagmar Srutkova, Anna Lange, Julia S. Frick, André Bleich and Bärbel Stecher
Frontiers in Microbiology, vol. 10, pp. 2999, Lausanne: Fontiers Research Foundation, 2020.
20212020
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression
Annika Hausmann, Desirée Böck, Petra Geiser, Dorothée L. Berthold, Stefan A. Fattinger, Markus Furter, Judith A. Bouman, Manja Barthel-Scherrer, Crispin M. Lang, Erik Bakkeren, Isabel Kolinko, Médéric Diard, Dirk Bumann, Emma Wetter Slack, Roland R. Regoes, Martin Pilhofer, Mikael E. Sellin and Wolf-Dietrich Hardt
Mucosal Immunology, New York, NY: Nature, 2020
2020Reproducible Colonization of Germ-Free Mice With the Oligo-Mouse-Microbiota in Different Animal Facilities
Claudia Eberl, Diana Ring, Philipp C. Münch, Markus Beutler, Marijana Basic, Emma C. Slack, Martin Schwarzer, Dagmar Srutkova, Anna Lange, Julia S. Frick, André Bleich and Bärbel Stecher
Frontiers in Microbiology, vol. 10, pp. 2999, Lausanne: Fontiers Research Foundation, 2020.
20202019
Growing, evolving and sticking in a flowing environment: understanding IgA interactions with bacteria in the gut
Daniel Hoces, Markus Arnoldini, Médéric Diard, Claude Loverdo and Emma Wetter Slack
Immunology, vol. 159: no. 1, pp. 52-62, Hoboken, NJ: Wiley, 2020
2019IgA and the intestinal microbiota: the importance of being specific
Oliver Pabst and Emma Slack
Mucosal Immunology, vol. 13: no. 1, pp. 12-21, New York, NY: Nature Publishing Group, 2020
2019Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
Cristina Gil-Cruz, Christian Perez-Shibayama, Angelina De Martin, Francesca Ronchi, Katrien van der Borght, Rebekka Niederer, Lucas Onder, Mechthild Lütge, Mario Novkovic, Veronika Nindl, Gustavo Ramos, Markus Arnoldini, Emma M.C. Wetter Slack, Valérie Boivin-Jahns, Roland Jahns, Madeleine Wyss, Catherine Mooser, Bart N. Lambrecht, Micha T. Maeder, Hans Rickli, Lukas Flatz, Urs Eriksson, Markus B. Geuking, Kathy D. McCoy and Burkhard Ludewig
Science, vol. 366: no. 6467, pp. 881-886, Washington, DC: American Association for the Advancement of Science, 2019
2019Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice
Sandra Y. Wotzka, Markus Kreuzer, Lisa Maier, Markus Arnoldini, Bidong D. Nguyen, Alexander O. Brachmann, Dorothée L. Berthold, Mirjam Zünd, Annika Hausmann, Erik Bakkeren, Daniel Hoces, Ersin Gül, Markus Beutler, Tamas Dolowschiak, Michael Zimmermann, Tobias Fuhrer, Kathrin Moor, Uwe Sauer, Athanasios Typas, Jörn Piel, Médéric Diard, Andrew J. Macpherson, Bärbel Stecher, Shinichi Sunagawa, Emma Wetter Slack and Wolf-Dietrich Hardt
Nature Microbiology, vol. 4: no. 12, pp. 2164-2174, London: Nature Publishing Group, 2019
2019Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut
Erik Bakkeren, Jana S. Huisman, Stefan A. Fattinger, Annika Hausmann, Markus Furter, Adrian Egli, Emma Wetter Slack, Mikael E. Sellin, Sebastian Bonhoeffer, Roland Robert Regös, Médéric Diard and Wolf-Dietrich Hardt
Nature, vol. 573: no. 7773, pp. 276-280, London: Nature Publishing Group, 2019
2019The antibody/microbiota interface in health and disease
Delphine Sterlin, Jehane Fadlallah, Emma Slack and Guy Gorochov
Mucosal Immunology, vol. 13: no. 1, pp. 3-11, New York, NY: Nature Publishing Group, 2020
2019Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis
Simone Herp, Sandrine Brugiroux, Debora Garzetti, Diana Ring, Lara M. Jochum, Markus Beutler, Claudia Eberl, Saib Hussain, Steffi Walter, Roman G. Gerlach, Hans-Joachim Ruscheweyh, Daniel Huson, Mikael E. Sellin, Emma Wetter Slack, Buck Hanson, Alexander Loy, John F. Baines, Philipp Rausch, Marijana Basic, André Bleich, David Berry and Bärbel Stecher
Cell Host & Microbe, vol. 25: no. 5, pp. 681-694.e8, Cambridge, MA: Cell Press, 2019
2019Enchained growth and cluster dislocation: A possible mechanism for microbiota homeostasis
Florence Bansept, Kathrin Schumann-Moor, Médéric Diard, Wolf-Dietrich Hardt, Emma Wetter Slack and Claude Loverdo
PLoS Computational Biology, vol. 15: no. 5, pp. e1006986, San Francisco, CA: Public Library of Science, 2019
2019Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity
Maria Martinez-Lopez, Salvador Iborra, Ruth Conde-Garrosa, Annalaura Mastrangelo, Camille Danne, Elizabeth R. Mann, Delyth M. Reid, Valérie Gaboriau-Routhiau, Maria Chaparro, Maria P. Lorenzo, Lara Minnerup, Paula Saz-Leal, Emma Wetter Slack, Benjamin Kemp, Javier P. Gisbert, Andrzej Dzionek, Matthew J. Robinson, Francisco J. Rupérez, Nadine Cerf-Bensussan, Gordon D. Brown, David Bernardo, Salomé LeibundGut-Landmann and David Sancho
Immunity, vol. 50: no. 2, pp. 446-461.e9, Cambridge, MA: Cell Press, 2019
2019ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens
Michele Proietti, Lisa Perruzza, Daniela Scribano, Giovanni Pellegrini, Rocco D'Antuono, Francesco Strati, Marco Raffaelli, Santiago F. Gonzalez, Marcus Thelen, Wolf-Dietrich Hardt, Emma Wetter Slack, Mauro Nicoletti and Fabio Grassi
Nature Communications, vol. 10, pp. 250, London: Nature Publishing Group, 2019
20192017
High-avidity IgA protects the intestine by enchaining growing bacteria
Kathrin Moor, Médéric Diard, Mikael E. Sellin, Boas Felmy, Sandra Y. Wotzka, Albulena Toska, Erik Bakkeren, Markus Arnoldini, Florence Bansept, Alma Dal Co, Tom Völler, Andrea Minola, Blanca Fernandez-Rodriguez, Gloria Agatic, Sonia Barbieri, Luca Piccoli, Costanza Casiraghi, Davide Corti, Antonio Lanzavecchia, Roland R. Regoes, Claude Loverdo, Roman Stocker, Douglas R. Brumley, Wolf-Dietrich Hardt and Emma Wetter Slack
Nature, vol. 544: no. 7651, pp. 498-502, London: Nature Publishing Group, 2017
2017Inflammation boosts bacteriophage transfer between Salmonella spp
Médéric Diard, Erik Bakkeren, Jeffrey K. Cornuault, Kathrin Moor, Annika Hausmann, Mikael E. Sellin, Claude Loverdo, Abram Aertsen, Martin Ackermann, Marianne De Paepe, Emma Wetter Slack and Wolf-Dietrich Hardt
Science, vol. 355: no. 6330, pp. 1211-1215, Washington, DC: American Association for the Advancement of Science, 2017
20172016
Analysis of bacterial-surface-specific antibodies in body fluids using bacterial flow cytometry
Kathrin Moor, Jehane Fadlallah, Albulena Toska, Delphine Sterlin, Maria L. Balmer, Andrew J. Macpherson, Guy Gorochov, Martin Larsen and Emma Wetter Slack
Nature Protocols, vol. 11: no. 8, pp. 1531-1553, London: Nature Publishing Group, 2016
2016Memory CD8+ T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function
Maria L. Balmer, Eric H. Ma, Glenn R. Bantug, Jasmin Grählert, Simona Pfister, Timo Glatter, Annaise Jauch, Sarah Dimeloe, Emma Wetter Slack, Philippe Dehio, Magdalena A. Krzyzaniak, Carolyn G. King, Anne-Valerie Burgener, Marco Fischer, Leyla Develioglu, Reka Belle, Mike Recher, Weldy V. Bonilla, Andrew J. Macpherson, Siegfried Hapfelmeier, Russell G. Jones and Christoph Hess
Immunity, vol. 44: no. 6, pp. 1312-1324, Cambridge MA, USA: Cell Press, 2016
2016Peracetic acid treatment generates potent inactivated oral vaccines from a broad range of culturable bacterial species
Emma Wetter Slack, Kathrin Moor, Sandra Y. Wotzka, Albulena Toska, Diard Médéric, Siegfried Hapfelmeier and Emma Wetter Slack
Frontiers in Immunology, vol. 7, pp. 34, Lausanne: Frontiers Research Foundation, 2016
20162015
What makes a bacterial oral vaccine a strong inducer of high-affinity IgA responses?
Kathrin Moor and Emma Wetter Slack
Antibodies, vol. 4: no. 4, pp. 295-313, Basel: MDPI, 2015
20152014
Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis
Lisa Maier, Médéric Diard, Mikael E. Sellin, Elsa-Sarah Chouffane, Kerstin Trautwein-Weidner, Balamurugan Periaswamy, Emma Wetter Slack, Tamas Dolowschiak, Bärbel Stecher, Claude Loverdo, Roland R. Regoes and Wolf-Dietrich Hardt
PLoS pathogens, vol. 10: no. 12, pp. e1004557, Lawrence, KS: Public Library of Science (PLoS), 2014
2014ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism
Michele Proietti, Vanessa Cornacchione, Tanja Rezzonico Jost, Andrea Romagnani, Caterina E. Faliti, Lisa Perruzza, Rosita Rigoni, Enrico Radaelli, Flavio Caprioli, Silvia Preziuso, Barbara Brannetti, Marcus Thelen, Kathy D. McCoy, Emma Wetter Slack, Elisabetta Traggiai and Fabio Grassi
Immunity, vol. 41: no. 5, pp. 789-801, Cambridge, MA: Elsevier, 2014
2014Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling
Maria L. Balmer, Christian M. Schurch, Yasuyuki Saito, Markus B. Geuking, Hai Li, Miguelangel Cuenca, Larisa V. Kovtonyuk, Kathy D. McCoy, Siegfried Hapfelmeier, Adrian F. Ochsenbein, Markus G. Manz, Emma Wetter Slack and Andrew J. Macpherson
The Journal of Immunology, vol. 193: no. 10, pp. 5273-5283, Bethesda, MD: AAI, 2014
2014B cells as a critical node in the microbiota-host immune system network
Emma Wetter Slack, Maria L. Balmer and Andrew J. Macpherson
Immunological reviews, vol. 260: no. 1, pp. 50-66, Oxford: Wiley-Blackwell, 2014
2014The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota
M.L. Balmer, Emma Wetter Slack, A. de Gottardi, M.A. Lawson, S. Hapfelmeier, L. Miele, A. Grieco, H. Van Vlierberghe, R. Fahrner, N. Patuto, C. Bernsmeier, F. Ronchi, M. Wyss, D. Stroka, N. Dickgreber, M.H. Heim, K.D. McCoy and A.J. Macpherson
Science Translational Medicine, vol. 6: no. 237, pp. 237ra66, Washington, DC: American Association for the Advancement of Science, 2014
2014Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment
Patrick Kaiser, Roland R. Regoes, Tamas Dolowschiak, Sandra Y. Wotzka, Jette Lengefeld, Emma Wetter Slack, Andrew J. Grant, Martin Ackermann and Wolf-Dietrich Hardt
PLoS Biology, vol. 12: no. 2, pp. e1001793, Lawrence, KS: Public Library of Science, 2014
20142013
NADPH Oxidase Deficient Mice Develop Colitis and Bacteremia upon Infection with Normally Avirulent, TTSS-1- and TTSS-2-Deficient Salmonella Typhimurium
Boas Felmy, Pascal Songhet, Emma Wetter Slack, Andreas J. Müller, Marcus Kremer, Laurye Van Maele, Delphine Cayet, Mathias Heikenwalder, Jean-Claude Sirard and Wolf-Dietrich Hardt
PLoS ONE, vol. 8: no. 10, pp. e77204, S.l.: Public Library of Science, 2013
2013Lymph Node Colonization Dynamics after Oral Salmonella Typhimurium Infection in Mice
Patrick Kaiser, Emma Wetter Slack, Andrew J. Grant, Wolf-Dietrich Hardt and Roland R. Regoes
PLoS pathogens, vol. 9: no. 9, pp. e1003532, Lawrence, KS: Public Library of Science (PLoS), 2013
2013Splicing defect of CD33 and inflammatory syndrome associated with occult bacterial infection
Maria L. Balmer, Beat Trüeb, Lei Zhuang, Emma Wetter Slack, Helmut Beltraminelli and Peter M. Villiger
Journal of Allergy and Clinical Immunology, vol. 132: no. 2, pp. 490-493, St. Louis, MO: Mosby, 2013
2013CD62L (L-Selectin) Shedding for Assessment of Perioperative Immune Sensitivity in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass
Gabor Erdoes, Maria L. Balmer, Emma Wetter Slack, Istvan Kocsis, Lutz E. Lehmann, Balthasar Eberle, Frank Stuber and Malte Book
PLoS ONE, vol. 8: no. 1, pp. e53045, Public Library Science, 2013
20132012
Live Attenuated S. Typhimurium Vaccine with Improved Safety in Immuno-Compromised Mice
Balamurugan Periaswamy, Lisa Maier, Vikalp Vishwakarma, Emma Wetter Slack, Marcus Kremer, Helene L. Andrews-Polymenis, Michael McClelland, Andrew J. Grant, Mrutyunjay Suar and Wolf-Dietrich Hardt
PLoS ONE, vol. 7: no. 9, pp. e45433, Lawrence, KS, USA: Public Library of Science, 2012
2012Promotion of liver regeneration by natural killer cells in a murine model is dependent on extracellular adenosine triphosphate phosphohydrolysis
Nadine Graubardt, René Fahrner, Markus Trochsler, Adrian Keogh, Karin Breu, Cynthia Furer, Deborah Stroka, Simon C. Robson, Emma Wetter Slack, Daniel Candinas and Guido Beldi
Hepatology, vol. 57: no. 5, pp. 1969-1979, Hoboken, NJ: Wiley, 2013
2012Lymphotoxin beta receptor signaling promotes development of autoimmune pancreatitis
Gitta M. Seleznik, Theresia Reding, Franziska Romrig, Yasuyuki Saito, Alexander Mildner, Stephan Segerer, Li-Kang Sun, Stephan Regenass, Maciej Lech, Hans-Joachim Anders, Donal McHugh, Teru Kumagi, Yoichi Hiasa, Carolin Lackner, Johannes Haybaeck, Eliane Angst, Aurel Perren, Maria L. Balmer, Emma Wetter Slack, Andrew MacPherson, Markus G. Manz, Achim Weber, Jeffrey L. Browning, Melek C. Arkan, Thomas Rülicke, Adriano Aguzzi, Marco Prinz, Rolf Graf and Mathias Heikenwalder
Gastroenterology, vol. 143: no. 5, pp. 1361-1374, Philadelphia, PA: W.B. Saunders, 2012
2012A Novel Phage Element of Salmonella enterica Serovar Enteritidis P125109 Contributes to Accelerated Type III Secretion System 2-Dependent Early Inflammation Kinetics in a Mouse Colitis Model
Vikalp Vishwakarma, Balamurugan Periaswamy, Niladri Bhusan Pati, Emma Wetter Slack, Wolf-Dietrich Hardt and Mrutyunjay Suar
Infection and immunity, vol. 80: no. 9, pp. 3236-3246, Washington: American Society for Microbiology, 2012
2012Functional flexibility of intestinal IgA – broadening the fine line
Emma Wetter Slack, Maria Luisa Balmer, Jörg H. Fritz and Siegfried Hapfelmeier
Frontiers in Immunology, vol. 3, pp. 100, Lausanne: Frontiers Research Foundation, 2012
2012The habitat, double life, citizenship, and forgetfulness of IgA
Andrew J. Macpherson, Markus B. Geuking, Emma Wetter Slack, Siegfried Hapfelmeier and Kathy D. McCoy
Immunological reviews, vol. 245: no. 1, pp. 132-146, Oxford: Wiley-Blackwell, 2012
20122011
Intestinal bacterial colonization induces mutualistic regulatory T cell responses
Markus B. Geuking, Julia Cahenzli, Melissa A. Lawson, Derek C.K. Ng, Emma Wetter Slack, Siegfried Hapfelmeier, Kathy D. McCoy and Andrew J. Macpherson
Immunity, vol. 34: no. 5, pp. 794-806, Cambridge, MA: Cell Press, 2011
2011Systemic antibody responses to gut commensal bacteria during chronic HIV-1 infection
Anna Haas, Kathrin Zimmermann, Frederik Graw, Emma Wetter Slack, Peter Rusert, Bruno Ledergerber, Walter Bossart, Rainer Weber, Maria C. Thurnheer, Manuel Battegay and et al.
Gut, vol. 60: no. 11, pp. 1506-1519, BMJ Publ. Group, 2011
20112010
The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea
Kathrin Endt, Bärbel Stecher, Samuel Chaffron, Emma Wetter Slack, Nicolas Tchitchek, Arndt G. Benecke, Laurye Van Maele, Jean-Claude Sirard, Andreas J. Müller, Mathias Heikenwalder, Andrew J. Macpherson, Richard Strugnell, Christian von Mering and Wolf-Dietrich Hardt
PLoS pathogens, vol. 6: no. 9, pp. e1001097, Lawrence, KS: Public Library of Science (PLoS), 2010
2010Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
Siegfried Hapfelmeier, Melissa A.E. Lawson, Emma Wetter Slack, Jorum K. Kirundi, Maaike Stoel, Mathias Heikenwalder, Julia Cahenzli, Yuliya Velykoredko, Maria L. Balmer, Kathrin Endt, Markus B. Geuking, Roy Curtiss, Kathy D. McCoy and Andrew J. Macpherson
Science, vol. 328: no. 5986, pp. 1705-1709, Cambridge, MA: Science, 2010
20102009
The mucosal firewalls against commensal intestinal microbes
Andrew J. Macpherson, Emma Wetter Slack, Markus B. Geuking and Kathy D. McCoy
Seminars in Immunopathology, vol. 31: no. 2, pp. 145-149, Heidelberg: Springer, 2009
2009Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
Emma Wetter Slack, Siegfried Hapfelmeier, Bärbel Stecher, Yuliya Velykoredko, Maaike Stoel, Melissa A.E. Lawson, Markus B. Geuking, Bruce Beutler, Thomas F. Tedder, Wolf-Dietrich Hardt, Premysl Bercik, Elena F. Verdu, Kathy D. McCoy and Andrew J. Macpherson
Science, vol. 325: no. 5940, pp. 617-620, Washington, D.C.: American Association for the Advancement of Science, 2009
2009Host Responses to Intestinal Microbial Antigens in Gluten-Sensitive Mice
Jane M. Natividad, Xianxi Huang, Emma Wetter Slack, Jennifer Jury, Yolanda Sanz, Chella David, Emmanuel Denou, Pinchang Yang, Joseph Murray, Kathy D. McCoy and Elena F. Verdu
PLoS ONE, vol. 4: no. 7, pp. e6472, San Francisco, CA, USA: Public Library of Science, 2009
20092008
Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo
Alan G. Worsley, Salome LeibundGut-Landmann, Emma Wetter Slack, Li-Kun Phng, Holger Gerhardt, Caetano Reis e Sousa and Andrew S. MacDonald
European journal of immunology, vol. 38: no. 4, pp. 1043-1049, Weinheim: Wiley-VCH, 2008
20082007
The functional interactions of commensal bacteria with intestinal secretory IgA
Andrew J. Macpherson and Emma Wetter Slack
Current Opinion in Gastroenterology, vol. 23: no. 6, pp. 673-678, Philadelphia, PA: Lippincott Williams & Wilkins, 2007
2007Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan
Emma Wetter Slack, Matthew J. Robinson, Patricia Hernanz-Falcón, Gordon D. Brown, David L. Williams, Edina Schweighoffer, Victor L. Tybulewicz and Caetano Reis e Sousa
European journal of immunology, vol. 37: no. 6, pp. 1600-1612, Weinheim: Wiley-VCH, 2007
2007Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
Salomé LeibundGut-Landmann, Olaf Gross, Matthew J. Robinson, Fabiola Osorio, Emma Wetter Slack, S. Vicky Tsoni, Edina Schweighoffer, Victor Tybulewicz, Gordon D. Brown, Jürgen Ruland and Caetano Reis e Sousa
Nature immunology, vol. 8: no. 6, pp. 630-638, New York, NY: Nature Publ. Group, 2007
20072006
Myeloid C-type lectins in innate immunity
Matthew J. Robinson, David Sancho, Emma Wetter Slack, Salomé LeibundGut-Landmann and Caetano Reis e Sousa
Nature immunology, vol. 7: no. 12, pp. 1258-1265, New York, NY: Nature Publ. Group, 2006
20062005
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
Neil C. Rogers, Emma Wetter Slack, Alexander D. Edwards, Martijn A. Nolte, Oliver Schulz, Edina Schweighoffer, David L. Williams, Siamon Gordon, Victor L. Tybulewicz, Gordon D. Brown and Caetano Reis e Sousa
Immunity, vol. 22: no. 4, pp. 507-517, Cambridge, MA: Cell Press, 2005
20052003
Toll-like receptor expression in murine DC subsets: Lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines
Alexander D. Edwards, Sandra S. Diebold, Emma Wetter Slack, Hideyuki Tomizawa, Hiroaki Hemmi, Tsuneyasu Kaisho, Shizuo Akira and Caetano Reis e Sousa
European journal of immunology, vol. 33: no. 4, pp. 827-833, Weinheim: Wiley-VCH, 2003
2003